glutathione gpx4 The Selenoprotein Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities Validated by Mechanisms and Therapeutic Potential of

For overexpression studies, pLX304-NINJ1 cDNA with a V5 tag was sourced from DNASU (HsCD00436123 and HsCD00438752), pWPI-SLC7A11 cDNA with an HA tag from Addgene (#201643), and pCDH-TFRC-mApple cDNA from Addgene (#179384)

In 1996, Abe and Kimura reported a physiological role of H 2 S as a neurotransmitter and identified cystathionine -synthase (CBS) as an H 2 S-producing enzyme [5]

Evaluation of oxidative stress markers in patients with bipolar disorder revealed their increased values in serum and erythrocytes (Akarsu et al

A Vanquish Horizon UHPLC system coupled to a Q Exactive Plus MS (both Thermo Fisher Scientific) was used to detect glutarate or succinate

Ebbing M, Bleie , Ueland PM, Nordrehaug JE, Nilsen DW, Vollset SE, Refsum H, Pedersen EK, Nygrd O